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Conolidine’s analgesic outcomes stem from its conversation with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors within the central anxious system, conolidine modulates alternate molecular targets. A Science Advancements review uncovered that conolidine interacts While using the atypical chemokine receptor ACKR3/CXCR7,
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